dra

168

deoxyribose-phosphate aldolase

locus: BSU_39420

Molecular weight: 22.06 kDa

pI: 4.93

Protein length: 223 aa

Gene length: 672 bp

function: utilization of nucleotides as carbon source

product: deoxyribose-phosphate aldolase

essential: no

ec: 4.1.2.4

synonyms: dra, deoC

List of homologs in different organisms, belongs to COG0274 (Galperin et al., 2021)

Gene

Coordinates: 4,051,602  4,052,273

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The protein

Catalyzed reaction/ biological activity

• 2-deoxy-D-ribose 5-phosphate --> acetaldehyde + D-glyceraldehyde 3-phosphate (according to UniProt)

Protein family

• DeoC/FbaB aldolase family (single member, according to UniProt)

Structure

• [PDB|1MZH] (from ''Aquifex aeolicus'', 42% identity, 62% similarity)
• [AF|P39121]

[wiki|Localization]

• cytoplasm (according to Swiss-Prot)

Biological materials

Mutant

• BKE39420 ([gene|81CD1F97E887549F7FB742FCEF38B86B84383F5D|dra]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE39420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCTTCGCACACTTCCTT,  downstream forward: _UP4_TAAGAGCTGACGGAAGGCAG
• BKK39420 ([gene|81CD1F97E887549F7FB742FCEF38B86B84383F5D|dra]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK39420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCTTCGCACACTTCCTT,  downstream forward: _UP4_TAAGAGCTGACGGAAGGCAG

References

• 10666464,11065368,8550462,10074062