Dps

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  • Description: iron storage protein, general stress protein, resistance against ethanol stress and survival at low temperatures

Gene name dps
Synonyms ytkB
Essential no
Product mini-ferritin
Function iron storage
Gene expression levels in SubtiExpress: dps
MW, pI 16 kDa, 4.444
Gene length, protein length 435 bp, 145 aa
Immediate neighbours ytkC, ytzI
Sequences Protein DNA DNA_with_flanks
Genetic context
Dps context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Dps expression.png
























Categories containing this gene/protein

acquisition of iron, iron metabolism, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU30650

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: dps family (according to Swiss-Prot)
  • Paralogous protein(s): MrgA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Emilia Chiancone, Pierpaolo Ceci, Andrea Ilari, Frederica Ribacchi, Simonetta Stefanini
Iron and proteins for iron storage and detoxification.
Biometals: 2004, 17(3);197-202
[PubMed:15222465] [WorldCat.org] [DOI] (P p)

Original publications

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

H Antelmann, S Engelmann, R Schmid, A Sorokin, A Lapidus, M Hecker
Expression of a stress- and starvation-induced dps/pexB-homologous gene is controlled by the alternative sigma factor sigmaB in Bacillus subtilis.
J Bacteriol: 1997, 179(23);7251-6
[PubMed:9393687] [WorldCat.org] [DOI] (P p)

M Bozzi, G Mignogna, S Stefanini, D Barra, C Longhi, P Valenti, E Chiancone
A novel non-heme iron-binding ferritin related to the DNA-binding proteins of the Dps family in Listeria innocua.
J Biol Chem: 1997, 272(6);3259-65
[PubMed:9013563] [WorldCat.org] [DOI] (P p)