dppA

dppA
168

D-alanyl-aminopeptidase

locus
BSU_12920
Molecular weight
30.09 kDa
pI
5.19
Protein length
Gene length
function
degradation of cell wall peptides
product
D-alanyl-aminopeptidase
essential
no
ec
null
synonyms
dppA, dciAA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2362 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,360,401  1,361,225
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The protein
Protein family
peptidase M55 family (single member, according to UniProt)
Structure
[PDB|1HI9]
[AF|P26902]
Modification
phosphorylated on ser/ thr/ tyr [Pubmed|16493705]
Expression and Regulation
Operons
genes
[gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]-[gene|062AE5FB4C778178A7F6833CB8BD9D631E461E89|dppB]-[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]-[gene|7FA72D949B930A3C7FF0391CC6CCC58EEFCA839A|dppD]-[gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]
description
[Pubmed|1766371]
regulation
repressed by glucose (2.9-fold) [Pubmed|12850135]
regulatory mechanism
[protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY]: repression, [Pubmed|7783641], in [regulon|protein:90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|1766371], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]→[gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]

2024-03-16 03:30:21

Jstuelk

58

09ee4083370400f9df0298a2b88ab5c0bbf1df43

5AB4A35A00613327500FE4CC530C2BFA97A6C07B

genes
[gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]-[gene|062AE5FB4C778178A7F6833CB8BD9D631E461E89|dppB]-[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]-[gene|7FA72D949B930A3C7FF0391CC6CCC58EEFCA839A|dppD]-[gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]-[gene|C4F85F85F0C99A59145961E34B19D3AD03D2BC22|ykfA]-[gene|77EFC47449D8CC17651ED61C41AC605FCEF01270|ykfB]-[gene|D40ECAE51D9E4791C6FAAA25E2E0D0591D9FAA55|ykfC]-[gene|BB94F5388A0D1FF025E5A88A7E10AE7E4C489E5F|ykfD]
description
[pubmed|22383849]
regulatory mechanism
[protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY]: repression, [Pubmed|12618455], in [regulon|protein:90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY regulon]
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[gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]->[gene|BB94F5388A0D1FF025E5A88A7E10AE7E4C489E5F|ykfD]

2024-03-12 10:58:41

Bzhu

85

9978370314fc05087eca13c4f3ce94e92ce93ff2

E2A0CC9BE866DBD9F0E3A5F48EE05465C14EFD9D

Biological materials
Mutant
BKE12920 ([gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE12920 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAACGCTCCTCCTTTTTT,  downstream forward: _UP4_TTCTGCTAAAGGGGTGTTTT
BKK12920 ([gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK12920 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAACGCTCCTCCTTTTTT,  downstream forward: _UP4_TTCTGCTAAAGGGGTGTTTT
References
18083814,12618455,1766371,19602397,7783641,1766371,12850135,16493705

9E922F0006DF9E84A8D5B51E9FC35B669872FF90

Page visits: 3194

Time of last update: 2024-03-28 13:42:05

Author of last update: Christoph.elfmann