Difference between revisions of "DivIC"

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(Extended information on the protein)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''  
+
* '''[[SubtInteract|Interactions]]:'''
 
** [[DivIC]]-[[FtsL]] {{PubMed|10844672}}
 
** [[DivIC]]-[[FtsL]] {{PubMed|10844672}}
 
** [[PbpB]]-[[DivIB]]-([[FtsL]]-[[DivIC]])2 {{PubMed|20870765}}, as part of the [[divisome]]
 
** [[PbpB]]-[[DivIB]]-([[FtsL]]-[[DivIC]])2 {{PubMed|20870765}}, as part of the [[divisome]]
  
* '''Localization:'''  membrane bound [http://www.ncbi.nlm.nih.gov/sites/entrez/9426141 PubMed]
+
* '''[[Localization]]:'''  membrane bound [http://www.ncbi.nlm.nih.gov/sites/entrez/9426141 PubMed]
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 12:21, 10 August 2011

  • Description: cell-division initiation protein (septum formation), component of septosome (with DivIB)

Gene name divIC
Synonyms
Essential yes PubMed
Product cell-division protein
Function septum formation
Interactions involving this protein in SubtInteract: DivIC
MW, pI 14 kDa, 9.968
Gene length, protein length 375 bp, 125 aa
Immediate neighbours yabQ, yabR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DivIC context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell division, sporulation proteins, cell envelope stress proteins (controlled by SigM, W, X, Y), essential genes, membrane proteins

This gene is a member of the following regulons

SigE regulon, SigM regulon, SigW regulon, SigX regulon

The gene

Basic information

  • Locus tag: BSU00620

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: stabilizes FtsL against RasP cleavage PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed during sporulation (SigE) PubMed and under stress conditions
  • Regulatory mechanism:
  • Additional information: there are about 50,000 molecules of DivIC per cell PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed