divIC

168

cell-division initiation protein (septum formation), component of septosome (with [protein|B66FC02948DABBCE64DE2629D6E33E05647B4EEF|divIB])

locus: BSU_00620

Molecular weight: 14.58 kDa

pI: 9.97

Protein length: 125 aa

Gene length: 378 bp

function: septum formation

product: cell-division protein, member of the [wiki|divisome]

essential: yes

synonyms: divIC

List of homologs in different organisms, belongs to COG2919 (Galperin et al., 2021)

Gene

Coordinates: 69,168 → 69,545

Phenotypes of a mutant

• essential [Pubmed|12682299]

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The protein

Catalyzed reaction/ biological activity

• stabilizes [protein|79712F4CF884A660C71B45B3397AEFA5C0AFA683|ftsL] against [protein|CB50289535EA537F63BADD459BD11AA7759A6658|rasP] cleavage [Pubmed|20644139]

Structure

• [AF|P37471]

[wiki|Localization]

• membrane bound [Pubmed|9426141]

Expression and Regulation

additional information

• there are about 50,000 molecules of DivIC per cell [pubmed|9426141]

Biological materials

FLAG-tag construct

• GP2006 ''divIC-3xFLAG ermC'' (based on [wiki|pGP1087]), available in [wiki|Jörg Stülke]'s lab

References

Reviews

• 35638784

Original Publications

• 18179421,16936019,10217758,9720875,8113187,10323866,9426141,10852898,10844672,11283287,11994149,20870765,25176632,20644139,29443967,33077634,33737746