dgkB

dgkB
168

diacylglycerol kinase

locus
BSU_06720
Molecular weight
33.18 kDa
pI
5.64
Protein length
Gene length
function
biosynthesis of lipoteichoic acid
product
diacylglycerol kinase
essential
no
ec
2.7.1.107
synonyms
dgkB, yerQ, dagK

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1597 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
736,436  737,347
Phenotypes of a mutant
the mutant tends to acquire suppressor mutations that result in improved growth [Pubmed|28189581]
essential [Pubmed|12682299], non-essential according to [Pubmed|28189581]
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The protein
Catalyzed reaction/ biological activity
1,2-diacyl-sn-glycerol + ATP --> 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+ (according to UniProt)
Protein family
diacylglycerol/lipid kinase family (with [protein|88AECCE90DC0D6C92C61AB8860A31A830A8DAC42|bmrU] and [protein|ED4C1EA16FF96DA20F12B972CD2458FA3B49DDA5|ytlR], according to UniProt)
[wiki|Domains]
DAGKc domain (aa 1-132) (according to UniProt)
Structure
[PDB|3S40] (from ''B. anthracis'', 32% identity, 68% similarity)
[AF|O31502]
Paralogous protein(s)
[protein|88AECCE90DC0D6C92C61AB8860A31A830A8DAC42|bmrU]
Expression and Regulation
Operons
genes
[gene|943294ACA74067A8549056699E08DF5B82337976|dgkB]-[gene|B97ABE3233A27A7C8273ED9A1E688247DD37FD12|rlmCD]
description
[Pubmed|22383849]
Open in new tab

[gene|943294ACA74067A8549056699E08DF5B82337976|dgkB]→[gene|B97ABE3233A27A7C8273ED9A1E688247DD37FD12|rlmCD]

2024-03-11 04:44:58

Jstuelk

60

c4890a496ded0653f7505864ebeaa248fc91af7f

322B8BEE164A821FAFE0FA8F102DB8F2A1E931B4

genes
[gene|943294ACA74067A8549056699E08DF5B82337976|dgkB]-[gene|B97ABE3233A27A7C8273ED9A1E688247DD37FD12|rlmCD]-[gene|5B5014A68D777DB79179904D5FD3D14DEE0BF1F4|yefC]-[gene|D3F00747006D974A8635D4391E0C261A3276E6AB|dnmA]-[gene|2E55D086DD5023B98929FB8B61238C00E66B8BCB|yeeB]-[gene|DB1AAC91947A6008F631266E5CC85B58703AFD9D|yeeC]
description
[Pubmed|22383849]
Open in new tab

[gene|943294ACA74067A8549056699E08DF5B82337976|dgkB]→[gene|DB1AAC91947A6008F631266E5CC85B58703AFD9D|yeeC]

2024-03-10 08:58:30

Jstuelk

75

ff916330f6b5023fdc317a5fb342282b6227f373

336CDC790AAC5927B58A940F2B9646F19FD7FCCD

Biological materials
Mutant
MGNA-B448 (yerQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1447 NBRP B. subtilis, Japan]
GP1391 ''dgkB::cat ltaS::aphA3'', available in [wiki|Jörg Stülke]'s lab
BKE06720 ([gene|943294ACA74067A8549056699E08DF5B82337976|dgkB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06720 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATCTCATCATCCTACT,  downstream forward: _UP4_TAAAACTTGGCTTGGTAAGC
BKK06720 ([gene|943294ACA74067A8549056699E08DF5B82337976|dgkB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06720 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATCTCATCATCCTACT,  downstream forward: _UP4_TAAAACTTGGCTTGGTAAGC
References
Reviews
24819367
Original Publications
17535816,22451476,28189581

943294ACA74067A8549056699E08DF5B82337976

Page visits: 2840

Time of last update: 2024-03-28 20:51:00

Author of last update: Jstuelk