Difference between revisions of "DgkA"

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(Additional information)
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|style="background:#ABCDEF;" align="center"| '''Product''' || undecaprenol kinase
 
|style="background:#ABCDEF;" align="center"| '''Product''' || undecaprenol kinase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of peptidoglycan
+
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 7.128   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 7.128   

Revision as of 17:52, 3 March 2010

  • Description: undecaprenol kinase

Gene name dgkA
Synonyms yqxF
Essential no
Product undecaprenol kinase
Function unknown
MW, pI 12 kDa, 7.128
Gene length, protein length 342 bp, 114 aa
Immediate neighbours cdd, yqfG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DgkA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU25310

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial diacylglycerol kinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

The gene is annotated in KEGG/MetaCyc/Swiss-Prot as diacylglycerol kinase EC 2.7.1.107. However, in the recently published paper (July 2007) by Jerga et al PubMed, the authors confirmed that dgkA is not a diacylglycerol kinase (DagK) but rather an undecaprenol kinase. This annotation was removed from Swiss-Prot as of November 2009. PubMed

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Agoston Jerga, Ying-Jie Lu, Gustavo E Schujman, Diego de Mendoza, Charles O Rock
Identification of a soluble diacylglycerol kinase required for lipoteichoic acid production in Bacillus subtilis.
J Biol Chem: 2007, 282(30);21738-45
[PubMed:17535816] [WorldCat.org] [DOI] (P p)

Samuel Amiteye, Kazuo Kobayashi, Daisuke Imamura, Shigeo Hosoya, Naotake Ogasawara, Tsutomu Sato
Bacillus subtilis diacylglycerol kinase (DgkA) enhances efficient sporulation.
J Bacteriol: 2003, 185(17);5306-9
[PubMed:12923107] [WorldCat.org] [DOI] (P p)