Difference between revisions of "DgcP"
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || diguanylate cyclase | |style="background:#ABCDEF;" align="center"| '''Product''' || diguanylate cyclase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of c-di-GMP |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29650 dgcP] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29650 dgcP] | ||
| Line 64: | Line 64: | ||
* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** synthesis of c-di-GMP from two molecules of GTP {{PubMed|23893111}} | ||
* '''Protein family:''' | * '''Protein family:''' | ||
| Line 74: | Line 75: | ||
* '''Domains:''' | * '''Domains:''' | ||
| + | ** contains an N-terminal GAF domain {{PubMed|23893111}} | ||
** contains a C-terminal GGDEF domain {{PubMed|22821967}} | ** contains a C-terminal GGDEF domain {{PubMed|22821967}} | ||
Revision as of 12:10, 10 August 2013
- Description: diguanylate cyclase
| Gene name | dgcP |
| Synonyms | ytrP |
| Essential | no |
| Product | diguanylate cyclase |
| Function | synthesis of c-di-GMP |
| Gene expression levels in SubtiExpress: dgcP | |
| MW, pI | 65 kDa, 5.695 |
| Gene length, protein length | 1737 bp, 579 aa |
| Immediate neighbours | ytsP, rpsD |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
metabolism of signalling nucleotides
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29650
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- synthesis of c-di-GMP from two molecules of GTP PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34325
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Xiaohui Gao, Sampriti Mukherjee, Paige M Matthews, Loubna A Hammad, Daniel B Kearns, Charles E Dann
Functional characterization of core components of the Bacillus subtilis cyclic-di-GMP signaling pathway.
J Bacteriol: 2013, 195(21);4782-92
[PubMed:23893111]
[WorldCat.org]
[DOI]
(I p)
Yun Chen, Yunrong Chai, Jian-hua Guo, Richard Losick
Evidence for cyclic Di-GMP-mediated signaling in Bacillus subtilis.
J Bacteriol: 2012, 194(18);5080-90
[PubMed:22821967]
[WorldCat.org]
[DOI]
(I p)
