DegR

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  • Description: regulation of degradative enzyme production

Gene name degR
Synonyms prtR
Essential no
Product positive effector of DegU-phosphate stability
Function control of DegU activity
MW, pI 6 kDa, 5.158
Gene length, protein length 180 bp, 60 aa
Immediate neighbours cspD, ypzA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DegR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DegR expression.png
























Categories containing this gene/protein

transcription factors and their control

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

  • Locus tag: BSU21940

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

M Ogura, Y Ohshiro, S Hirao, T Tanaka
A new Bacillus subtilis gene, med, encodes a positive regulator of comK.
J Bacteriol: 1997, 179(20);6244-53
[PubMed:9335269] [WorldCat.org] [DOI] (P p)

M Ogura, T Tanaka
Bacillus subtilis ComK negatively regulates degR gene expression.
Mol Gen Genet: 1997, 254(2);157-65
[PubMed:9108277] [WorldCat.org] [DOI] (P p)

M Ogura, T Tanaka
Transcription of Bacillus subtilis degR is sigma D dependent and suppressed by multicopy proB through sigma D.
J Bacteriol: 1996, 178(1);216-22
[PubMed:8550420] [WorldCat.org] [DOI] (P p)

K Mukai, M Kawata-Mukai, T Tanaka
Stabilization of phosphorylated Bacillus subtilis DegU by DegR.
J Bacteriol: 1992, 174(24);7954-62
[PubMed:1459944] [WorldCat.org] [DOI] (P p)

M Yang, H Shimotsu, E Ferrari, D J Henner
Characterization and mapping of the Bacillus subtilis prtR gene.
J Bacteriol: 1987, 169(1);434-7
[PubMed:3098734] [WorldCat.org] [DOI] (P p)

Y Nagami, T Tanaka
Molecular cloning and nucleotide sequence of a DNA fragment from Bacillus natto that enhances production of extracellular proteases and levansucrase in Bacillus subtilis.
J Bacteriol: 1986, 166(1);20-8
[PubMed:3082853] [WorldCat.org] [DOI] (P p)