Difference between revisions of "DegR"
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || positive effector of DegU-phosphate stability | + | |style="background:#ABCDEF;" align="center"| '''Product''' || positive effector of [[DegU]]-phosphate stability |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of DegU activity | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[DegU]] activity |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 6 kDa, 5.158 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 6 kDa, 5.158 | ||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[degR]]'' | + | * '''Operon:''' ''[[degR]]'' {{PubMed|3082853}} |
| − | * '''[[Sigma factor]]:''' [[SigD]] | + | * '''[[Sigma factor]]:''' [[SigD]] {{PubMed|8550420}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 118: | Line 118: | ||
=References= | =References= | ||
| − | <pubmed>9335269,1459944,9108277,3098734,8550420,, </pubmed> | + | <pubmed>9335269,1459944,9108277,3098734,8550420,3082853 , </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:01, 26 October 2009
- Description: regulation of degradative enzyme production
| Gene name | degR |
| Synonyms | prtR |
| Essential | no |
| Product | positive effector of DegU-phosphate stability |
| Function | control of DegU activity |
| MW, pI | 6 kDa, 5.158 |
| Gene length, protein length | 180 bp, 60 aa |
| Immediate neighbours | cspD, ypzA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU21940
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P68731
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
M Ogura, Y Ohshiro, S Hirao, T Tanaka
A new Bacillus subtilis gene, med, encodes a positive regulator of comK.
J Bacteriol: 1997, 179(20);6244-53
[PubMed:9335269]
[WorldCat.org]
[DOI]
(P p)
M Ogura, T Tanaka
Bacillus subtilis ComK negatively regulates degR gene expression.
Mol Gen Genet: 1997, 254(2);157-65
[PubMed:9108277]
[WorldCat.org]
[DOI]
(P p)
M Ogura, T Tanaka
Transcription of Bacillus subtilis degR is sigma D dependent and suppressed by multicopy proB through sigma D.
J Bacteriol: 1996, 178(1);216-22
[PubMed:8550420]
[WorldCat.org]
[DOI]
(P p)
K Mukai, M Kawata-Mukai, T Tanaka
Stabilization of phosphorylated Bacillus subtilis DegU by DegR.
J Bacteriol: 1992, 174(24);7954-62
[PubMed:1459944]
[WorldCat.org]
[DOI]
(P p)
M Yang, H Shimotsu, E Ferrari, D J Henner
Characterization and mapping of the Bacillus subtilis prtR gene.
J Bacteriol: 1987, 169(1);434-7
[PubMed:3098734]
[WorldCat.org]
[DOI]
(P p)
Y Nagami, T Tanaka
Molecular cloning and nucleotide sequence of a DNA fragment from Bacillus natto that enhances production of extracellular proteases and levansucrase in Bacillus subtilis.
J Bacteriol: 1986, 166(1);20-8
[PubMed:3082853]
[WorldCat.org]
[DOI]
(P p)
