Difference between revisions of "DctB"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=DctB DctB]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=DctB DctB]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=dctB dctB]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 4.889   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 4.889   

Revision as of 10:11, 7 January 2014

  • Description: C4-dicarboxylate binding protein, co-sensor for DctS

Gene name dctB
Synonyms ydbE
Essential no
Product C4-dicarboxylate binding protein
Function sensing of C4-dicarboxylates
Gene expression levels in SubtiExpress: dctB
Interactions involving this protein in SubtInteract: DctB
Metabolic function and regulation of this protein in SubtiPathways:
dctB
MW, pI 39 kDa, 4.889
Gene length, protein length 1050 bp, 350 aa
Immediate neighbours ydbD, dctS
Sequences Protein DNA DNA_with_flanks
Genetic context
DctB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DctB expression.png















Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU04440

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • not involved in C4-dicarboxylate transport PubMed
    • acts as co-sensor for DctS PubMed
  • Protein family: bacterial solute-binding protein 7 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sabrina Graf, Dominik Schmieden, Karolin Tschauner, Sabine Hunke, Gottfried Unden
The sensor kinase DctS forms a tripartite sensor unit with DctB and DctA for sensing C4-dicarboxylates in Bacillus subtilis.
J Bacteriol: 2014, 196(5);1084-93
[PubMed:24375102] [WorldCat.org] [DOI] (I p)

Kei Asai, Sang-Hoon Baik, Yasuhiro Kasahara, Shigeki Moriya, Naotake Ogasawara
Regulation of the transport system for C4-dicarboxylic acids in Bacillus subtilis.
Microbiology (Reading): 2000, 146 ( Pt 2);263-271
[PubMed:10708364] [WorldCat.org] [DOI] (P p)