Difference between revisions of "DapI"

From SubtiWiki
Jump to: navigation, search
(Expression and regulation)
Line 111: Line 111:
 
* '''Operon:'''  
 
* '''Operon:'''  
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dapL_1489753_1490877_1 ykuR] {{PubMed|22383849}}
+
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dapL_1489753_1490877_1 dapI] {{PubMed|22383849}}
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
Line 119: Line 119:
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
  
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =

Revision as of 12:12, 5 January 2014

  • Description: N-acetyl-diaminopimelate deacetylase

Gene name ykuR
Synonyms dapL
Essential yes PubMed
Product N-acetyl-diaminopimelate deacetylase
Function biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: dapI
Metabolic function and regulation of this protein in SubtiPathways:
Lys, Thr
MW, pI 41 kDa, 5.102
Gene length, protein length 1122 bp, 374 aa
Immediate neighbours ykuQ, ykuS
Sequences Protein DNA DNA_with_flanks
Genetic context
YkuR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkuR expression.png















Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, biosynthesis/ acquisition of amino acids, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU14190

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: N-acetyl-LL-2,6-diaminopimelate + H2O --> acetate + LL-2,6-diaminopimelate PubMed
  • Protein family: peptidase M20A family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Anne-Stéphanie Rueff, Arnaud Chastanet, Julia Domínguez-Escobar, Zhizhong Yao, James Yates, Maria-Victoria Prejean, Olivier Delumeau, Philippe Noirot, Roland Wedlich-Söldner, Sergio R Filipe, Rut Carballido-López
An early cytoplasmic step of peptidoglycan synthesis is associated to MreB in Bacillus subtilis.
Mol Microbiol: 2014, 91(2);348-62
[PubMed:24261876] [WorldCat.org] [DOI] (I p)