Difference between revisions of "DapI"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykuQ]]'', ''[[ykuS]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykuQ]]'', ''[[ykuS]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14190 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14190 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14190 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14190 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14190 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14190 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ykuR_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ykuR_context.gif]]

Revision as of 10:05, 14 May 2013

  • Description: N-acetyl-diaminopimelate deacetylase

Gene name ykuR
Synonyms dapL
Essential yes PubMed
Product N-acetyl-diaminopimelate deacetylase
Function biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: ykuR
Metabolic function and regulation of this protein in SubtiPathways:
Lys, Thr
MW, pI 41 kDa, 5.102
Gene length, protein length 1122 bp, 374 aa
Immediate neighbours ykuQ, ykuS
Sequences Protein DNA DNA_with_flanks
Genetic context
YkuR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkuR expression.png















Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, biosynthesis/ acquisition of amino acids, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU14190

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: N-acetyl-LL-2,6-diaminoheptanedioate + H2O = acetate + LL-2,6-diaminoheptanedioate (according to Swiss-Prot)
  • Protein family: peptidase M20A family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

The gene is annotated in KEGG as an ortholog of N-acetyldiaminopimelate deacetylase EC 3.5.1.47. In MetaCyc it is marked as “similar to hippurate hydrolase”. No EC annotation is available in Swiss-Prot. No literature/experimental evidence supporting the annotation is available. PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References