DapF

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  • Description: diaminopimelate epimerase

Gene name dapF
Synonyms yutL
Essential yes PubMed
Product diaminopimelate epimerase
Function biosynthesis of lysine and peptidoglycan
Metabolic function and regulation of this protein in SubtiPathways:
Lys, Thr
MW, pI 30 kDa, 4.506
Gene length, protein length 852 bp, 284 aa
Immediate neighbours sufA, yutK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DapF context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU32170

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate (according to Swiss-Prot)
  • Protein family: diaminopimelate epimerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2OTN (from Bacillus anthracis str. ames, 62% identity, 75% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References