DapF

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  • Description: diaminopimelate epimerase

Gene name dapF
Synonyms yutL
Essential yes PubMed
Product diaminopimelate epimerase
Function biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: dapF
Metabolic function and regulation of this protein in SubtiPathways:
Lys, Thr
MW, pI 30 kDa, 4.506
Gene length, protein length 852 bp, 284 aa
Immediate neighbours sufA, yutK
Sequences Protein DNA Advanced_DNA
Genetic context
DapF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DapF expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU32170

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate (according to Swiss-Prot)
  • Protein family: diaminopimelate epimerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2OTN (from Bacillus anthracis str. ames, 62% identity, 75% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References