dapF

dapF
168

diaminopimelate epimerase

locus
BSU_32170
Molecular weight
30.72 kDa
pI
4.51
Protein length
Gene length
function
biosynthesis of lysine and peptidoglycan
product
diaminopimelate epimerase
essential
yes
ec
5.1.1.7
synonyms
dapF, yutL

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0253 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,306,040  3,306,894
Phenotypes of a mutant
essential [Pubmed|12682299]
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The protein
Catalyzed reaction/ biological activity
LL-2,6-diaminoheptanedioate --> meso-2,6-diaminopimelate (according to UniProt)
Protein family
diaminopimelate epimerase family (single member, according to UniProt)
Structure
[PDB|2OTN] (from ''Bacillus anthracis str. ames'', 62% identity, 75% similarity)
[AF|O32114]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|185B6596F0468B76BCA85E8753063FAE83445E18|dapF]-[gene|94A3B5EF4ADCFA57A204B584B6D305A62E3E15AE|sufA]
description
[Pubmed|22383849]
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[gene|185B6596F0468B76BCA85E8753063FAE83445E18|dapF]→[gene|94A3B5EF4ADCFA57A204B584B6D305A62E3E15AE|sufA]

2024-03-16 07:27:16

Jstuelk

53

cb67469c37f698f5888cb5accc1ac921d00650b0

F8FF2423BEC3A4415C691F58C9990C193330CF09

Biological materials
Mutant
MGNA-B574 (yutL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1573 NBRP B. subtilis, Japan]

185B6596F0468B76BCA85E8753063FAE83445E18

Page visits: 2339

Time of last update: 2024-03-22 17:07:36

Author of last update: Melvin.boenninger