Difference between revisions of "DapB"

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= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
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{{SubtiWiki category|[[essential genes]]}}
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= This gene is a member of the following [[regulons]] =
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=The gene=
 
=The gene=
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
 
{{SubtiWiki category|[[essential genes]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 20:47, 8 December 2010

  • Description: dihydrodipicolinate reductase (NADPH)

Gene name dapB
Synonyms
Essential yes PubMed
Product dihydrodipicolinate reductase (NADPH)
Function biosynthesis of lysine and peptidoglycan
Metabolic function and regulation of this protein in SubtiPathways:
Lys, Thr
MW, pI 29 kDa, 5.057
Gene length, protein length 801 bp, 267 aa
Immediate neighbours mgsA, ypjD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DapB context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU22490

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = 2,3-dihydrodipicolinate + NAD(P)H (according to Swiss-Prot)
  • Protein family: glucose-6-phosphate dehydrogenase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1YL6 (from Mycobacterium tuberculosis, 46% identity, 67% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Operon and expression