Difference between revisions of "DapA"

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(Undo revision 129392 by Awynalaxa (talk))
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* '''Description:''' dihydrodipicolinate synthase <br/><br/>
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=[http://yxiwisewava.co.cc UNDER COSTRUCTION, PLEASE SEE THIS POST IN RESERVE COPY]=
 
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=[http://yxiwisewava.co.cc CLICK HERE]=
 
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* '''Description:''' dihydrodipicolinate synthase &lt;br/>&lt;br/>
 
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of lysine and peptidoglycan
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of lysine and peptidoglycan
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: &lt;br/>[http://subtiwiki.uni-goettingen.de/pathways/lys_threo.html Lys, Thr]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/lys_threo.html Lys, Thr]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 30 kDa, 4.928   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 30 kDa, 4.928   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[dapG]]'', ''[[rnjB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[dapG]]'', ''[[rnjB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&amp;#91;EMBLCDS:CAB13550&amp;#93;+-newId sequences] &lt;br/> (Barbe ''et al.'', 2009)'''
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13550&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
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|colspan="2" | '''Genetic context''' &lt;br/> [[Image:dapA_context.gif]]
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|colspan="2" | '''Genetic context''' <br/> [[Image:dapA_context.gif]]
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  &lt;div align="right"> &lt;small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]&lt;/small>&lt;/div>
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  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
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__TOC__
 
__TOC__
  
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&lt;br/>&lt;br/>&lt;br/>&lt;br/>&lt;br/>&lt;br/>
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<br/><br/><br/><br/><br/><br/>
  
 
=The gene=
 
=The gene=
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
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* '''Catalyzed reaction/ biological activity:''' L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H&lt;sub>2&lt;/sub>O (according to Swiss-Prot)  
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* '''Catalyzed reaction/ biological activity:''' L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H<sub>2</sub>O (according to Swiss-Prot)  
  
 
* '''Protein family:''' DHDPS family (according to Swiss-Prot)
 
* '''Protein family:''' DHDPS family (according to Swiss-Prot)
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=References=
 
=References=
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&lt;pubmed>8345520,,15699190 8098035,, &lt;/pubmed>
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<pubmed>8345520,,15699190 8098035,, </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 06:13, 24 November 2010

  • Description: dihydrodipicolinate synthase

Gene name dapA
Synonyms
Essential yes PubMed
Product dihydrodipicolinate synthase
Function biosynthesis of lysine and peptidoglycan
Metabolic function and regulation of this protein in SubtiPathways:
Lys, Thr
MW, pI 30 kDa, 4.928
Gene length, protein length 870 bp, 290 aa
Immediate neighbours dapG, rnjB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DapA context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU16770

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O (according to Swiss-Prot)
  • Protein family: DHDPS family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 3CPR (from Corynebacterium glutamicum, 39% identity, 58% similarity) PubMed
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

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