cysS

168

cysteine-tRNA synthetase

locus: BSU_00940

Molecular weight: 53.74 kDa

pI: 5.07

Protein length: 466 aa

Gene length: 1401 bp

function: translation

product: cysteine-tRNA synthetase

essential: yes

ec: 6.1.1.16

synonyms: cysS, snpA

List of homologs in different organisms, belongs to COG0215 (Galperin et al., 2021)

Gene

Coordinates: 113,450 → 114,850

Phenotypes of a mutant

• essential [Pubmed|12682299]

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The protein

Catalyzed reaction/ biological activity

• ATP + L-cysteine + tRNA^Cys --> AMP + diphosphate + L-cysteinyl-tRNA^Cys (according to UniProt)

Protein family

• [wiki|Class-I aminoacyl-tRNA synthetase family] (according to UniProt)

Structure

• [PDB|1U0B] (from ''Escherichia coli'', 42% identity, 56% similarity) [Pubmed|15489861]
• [AF|Q06752]

Modification

• phosphorylation on Ser-270 [Pubmed|17218307]

[wiki|Localization]

• cytoplasm (according to UniProt)

References

• 19258532,17218307,7510287