Difference between revisions of "CwlT"

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|style="background:#ABCDEF;" align="center"|'''Function''' || cell wall metabolism
 
|style="background:#ABCDEF;" align="center"|'''Function''' || cell wall metabolism
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU04970 cwlT]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU04970 cwlT]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 8.632   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 8.632   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yddG]]'', ''[[yddI]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yddG]]'', ''[[yddI]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12304&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU04970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU04970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU04970 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yddH_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yddH_context.gif]]

Revision as of 12:12, 13 May 2013


Gene name cwlT
Synonyms yddH
Essential
Product cell wall hydrolase
Function cell wall metabolism
Gene expression levels in SubtiExpress: cwlT
MW, pI 36 kDa, 8.632
Gene length, protein length 987 bp, 329 aa
Immediate neighbours yddG, yddI
Sequences Protein DNA Advanced_DNA
Genetic context
YddH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CwlT expression.png
























Categories containing this gene/protein

cell wall degradation/ turnover

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU04970

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: nlpC/p60 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • induced by mitomycin C PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Tatsuya Fukushima, Toshihiko Kitajima, Hiroyuki Yamaguchi, Qin Ouyang, Kazumi Furuhata, Hiroki Yamamoto, Toshio Shida, Junichi Sekiguchi
Identification and characterization of novel cell wall hydrolase CwlT: a two-domain autolysin exhibiting n-acetylmuramidase and DL-endopeptidase activities.
J Biol Chem: 2008, 283(17);11117-25
[PubMed:18305117] [WorldCat.org] [DOI] (P p)