Difference between revisions of "CwlK"

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Revision as of 08:35, 8 August 2012

  • Description: peptidoglycan hydrolytic L,D-endopeptidase

Gene name cwlK
Synonyms ycdD
Essential no
Product peptidoglycan hydrolytic L,D-endopeptidase
Function cell wall turnover
MW, pI 18 kDa, 5.66
Gene length, protein length 501 bp, 167 aa
Immediate neighbours ycdC, rapJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YcdD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CwlK expression.png
























Categories containing this gene/protein

cell wall degradation/ turnover, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU02810

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M15C family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Ciaran Condon, IBPC, Paris, France Homepage

Your additional remarks

References

Tatsuya Fukushima, Yang Yao, Toshihiko Kitajima, Hiroki Yamamoto, Junichi Sekiguchi
Characterization of new L,D-endopeptidase gene product CwlK (previous YcdD) that hydrolyzes peptidoglycan in Bacillus subtilis.
Mol Genet Genomics: 2007, 278(4);371-83
[PubMed:17588176] [WorldCat.org] [DOI] (P p)