CpgA

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  • Description: GTPase, activity stimulated by ribosomes, may be involved in ribosome maturation

Gene name cpgA
Synonyms yloQ
Essential no
Product GTPase
Function ribosome assembly, coordination of peptidoglycan deposition in the cell wall
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 33 kDa, 4.743
Gene length, protein length 894 bp, 298 aa
Immediate neighbours prkC, rpe
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YloQ context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU15780

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: engC GTPase domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated on Ser/ Thr by PrkC, dephosphorylated by PrpC PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Tony Wilkinson, York University, U.K. homepage

Your additional remarks

References

Reviews

Robert A Britton
Role of GTPases in bacterial ribosome assembly.
Annu Rev Microbiol: 2009, 63;155-76
[PubMed:19575570] [WorldCat.org] [DOI] (I p)

Original publications