Difference between revisions of "CotG"

From SubtiWiki
Jump to: navigation, search
Line 1: Line 1:
* '''Description:''' spore coat protein <br/><br/>
+
* '''Description:''' outer spore coat protein <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 37: Line 37:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
 
 
<br/><br/>
 
<br/><br/>
  
Line 49: Line 45:
 
{{SubtiWiki regulon|[[GerE regulon]]}},
 
{{SubtiWiki regulon|[[GerE regulon]]}},
 
{{SubtiWiki regulon|[[GerR regulon]]}},
 
{{SubtiWiki regulon|[[GerR regulon]]}},
 +
{{SubtiWiki regulon|[[SigE regulon]]}},
 
{{SubtiWiki regulon|[[SigK regulon]]}}
 
{{SubtiWiki regulon|[[SigK regulon]]}}
  
Line 96: Line 93:
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
 +
** outer spore coat, localization depends on [[CotE]]  {{PubMed|22171814}}
  
 
=== Database entries ===
 
=== Database entries ===
Line 114: Line 112:
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotG_3717238_3717825_1 cotG] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotG_3717238_3717825_1 cotG] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigK]] {{PubMed|15699190,7814326}}
+
* '''Sigma factor:''' [[SigE]] {{PubMed|15383836}}, [[SigK]] {{PubMed|15699190,7814326}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|15699190,7814326}}
+
** expressed late during sporulation in the mother cell ([[SigE]], [[SigK]], [[GerE]]) {{PubMed|15383836,15699190,7814326}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
Line 144: Line 142:
  
 
=References=
 
=References=
'''Additional publications:''' {{PubMed|21984783}}
+
<pubmed>12884008,7814326,9573176,14762006, 15699190 15621419 22171814 21984783 15383836</pubmed>
<pubmed>12884008,7814326,9573176,14762006, 15699190 15621419 </pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:31, 13 August 2013

  • Description: outer spore coat protein

Gene name cotG
Synonyms
Essential no
Product spore coat protein
Function resistance of the spore
Gene expression levels in SubtiExpress: cotG
Interactions involving this protein in SubtInteract: CotG
MW, pI 23 kDa, 10.673
Gene length, protein length 585 bp, 195 aa
Immediate neighbours cotH, ywrF
Sequences Protein DNA DNA_with_flanks
Genetic context
CotG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotG expression.png















Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

GerE regulon, GerR regulon, SigE regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU36070

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814] [WorldCat.org] [DOI] (I p)

Rosa Giglio, Renato Fani, Rachele Isticato, Maurilio De Felice, Ezio Ricca, Loredana Baccigalupi
Organization and evolution of the cotG and cotH genes of Bacillus subtilis.
J Bacteriol: 2011, 193(23);6664-73
[PubMed:21984783] [WorldCat.org] [DOI] (I p)

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Ritsuko Kuwana, Takashi Okumura, Hiromu Takamatsu, Kazuhito Watabe
The ylbO gene product of Bacillus subtilis is involved in the coat development and lysozyme resistance of spore.
FEMS Microbiol Lett: 2005, 242(1);51-7
[PubMed:15621419] [WorldCat.org] [DOI] (P p)

Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836] [WorldCat.org] [DOI] (I p)

Rita Zilhão, Mónica Serrano, Rachele Isticato, Ezio Ricca, Charles P Moran, Adriano O Henriques
Interactions among CotB, CotG, and CotH during assembly of the Bacillus subtilis spore coat.
J Bacteriol: 2004, 186(4);1110-9
[PubMed:14762006] [WorldCat.org] [DOI] (P p)

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)

A O Henriques, L R Melsen, C P Moran
Involvement of superoxide dismutase in spore coat assembly in Bacillus subtilis.
J Bacteriol: 1998, 180(9);2285-91
[PubMed:9573176] [WorldCat.org] [DOI] (P p)

M Sacco, E Ricca, R Losick, S Cutting
An additional GerE-controlled gene encoding an abundant spore coat protein from Bacillus subtilis.
J Bacteriol: 1995, 177(2);372-7
[PubMed:7814326] [WorldCat.org] [DOI] (P p)