Difference between revisions of "CorA"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU24740&redirect=T BSU24740]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yqxL.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yqxL.html]
Line 94: Line 95:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU24740&redirect=T BSU24740]
  
 
* '''Structure:'''
 
* '''Structure:'''

Revision as of 14:13, 2 April 2014

  • Description: general stress protein, similar to magnesium transporter

Gene name corA
Synonyms yqhC , yqxL
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: corA
Metabolic function and regulation of this protein in SubtiPathways:
metal ion homeostasis
MW, pI 37 kDa, 9.536
Gene length, protein length 951 bp, 317 aa
Immediate neighbours comGA, yqhB
Sequences Protein DNA DNA_with_flanks
Genetic context
YqxL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CorA expression.png















Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), general stress proteins (controlled by SigB), membrane proteins

This gene is a member of the following regulons

LexA regulon, SigB regulon

The gene

Basic information

  • Locus tag: BSU24740

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • there is no indication for an implication of CorA in Mg2+ uptake (based on mutant phenotypes, failure to complement mutants defective in Mg2+ uptake) PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Catherine A Wakeman, Jonathan R Goodson, Vineetha M Zacharia, Wade C Winkler
Assessment of the requirements for magnesium transporters in Bacillus subtilis.
J Bacteriol: 2014, 196(6);1206-14
[PubMed:24415722] [WorldCat.org] [DOI] (I p)

Nora Au, Elke Kuester-Schoeck, Veena Mandava, Laura E Bothwell, Susan P Canny, Karen Chachu, Sierra A Colavito, Shakierah N Fuller, Eli S Groban, Laura A Hensley, Theresa C O'Brien, Amish Shah, Jessica T Tierney, Louise L Tomm, Thomas M O'Gara, Alexi I Goranov, Alan D Grossman, Charles M Lovett
Genetic composition of the Bacillus subtilis SOS system.
J Bacteriol: 2005, 187(22);7655-66
[PubMed:16267290] [WorldCat.org] [DOI] (P p)

Hanne-Leena Hyyryläinen, Matti Sarvas, Vesa P Kontinen
Transcriptome analysis of the secretion stress response of Bacillus subtilis.
Appl Microbiol Biotechnol: 2005, 67(3);389-96
[PubMed:15856219] [WorldCat.org] [DOI] (P p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

Mary Ann Warren, Lisa M Kucharski, Alexander Veenstra, Liang Shi, Paul F Grulich, Michael E Maguire
The CorA Mg2+ transporter is a homotetramer.
J Bacteriol: 2004, 186(14);4605-12
[PubMed:15231793] [WorldCat.org] [DOI] (P p)

M Albano, R Breitling, D A Dubnau
Nucleotide sequence and genetic organization of the Bacillus subtilis comG operon.
J Bacteriol: 1989, 171(10);5386-404
[PubMed:2507524] [WorldCat.org] [DOI] (P p)