corA

168

general stress protein, similar to magnesium transporter

locus: BSU_24740

Molecular weight: 37.55 kDa

pI: 9.54

Protein length: 317 aa

Gene length: 954 bp

function: unknown

product: unknown

essential: no

synonyms: corA, yqhC, yqxL

List of homologs in different organisms, belongs to COG0598 (Galperin et al., 2021)

Gene

Coordinates: 2,560,489 → 2,561,442

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The protein

Catalyzed reaction/ biological activity

• there is no indication for an implication of [protein|F0CACEFB53F4BC38DF77A38C4D78BA3DBE96E21A|corA] in Mg² uptake (based on mutant phenotypes, failure to complement mutants defective in Mg² uptake) [Pubmed|24415722]

Protein family

• CorA metal ion transporter (MIT) (TC 1.A.35) family (together with [protein|D281B88EC444F8175AB50FB2CD24B51F4E2C96F8|yfjQ]) (according to UniProt)

Structure

• [PDB|5JTG] (from Themotoga maritima, C-terminal domain, aa 122-297, 28% identity)
• [AF|P40948]

[wiki|Localization]

• inner spore membrane [Pubmed|26731423]

Biological materials

Mutant

• MGNA-C473 (yqxL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2471 NBRP B. subtilis, Japan]
• BKE24740 (Δ[gene|F0CACEFB53F4BC38DF77A38C4D78BA3DBE96E21A|corA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE24740 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTCAAGCTCCTCCAAAC,  downstream forward: _UP4_TAGGATGTTTCATATTTTGT
• BKK24740 (Δ[gene|F0CACEFB53F4BC38DF77A38C4D78BA3DBE96E21A|corA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK24740 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTCAAGCTCCTCCAAAC,  downstream forward: _UP4_TAGGATGTTTCATATTTTGT

References

Reviews

• 24079267

Original Publications

• 15231793,15856219,2507524,16267290,15805528,24415722,26731423,35129435