Difference between revisions of "ComS"

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* '''Description:''' antiadaptor protein, assembly link between regulatory components of the competence signal transduction pathway <br/><br/>
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComK]] degradation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComK]] degradation
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU03500 comS]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComS ComS]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComS ComS]

Revision as of 15:00, 6 August 2012


Gene name comS
Synonyms
Essential no
Product antiadaptor protein (anti-MecA)
Function control of ComK degradation
Gene expression levels in SubtiExpress: comS
Interactions involving this protein in SubtInteract: ComS
MW, pI 5 kDa, 9.145
Gene length, protein length 138 bp, 46 aa
Immediate neighbours srfAB, srfAC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ComS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComS expression.png
























Categories containing this gene/protein

genetic competence, short peptides

This gene is a member of the following regulons

Abh regulon, CodY regulon, ComA regulon, PerR regulon, Spx regulon

The gene

Basic information

  • Locus tag: BSU03500

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • repressed during hydrogen peroxide stress (PerR) PubMed
    • expressed at high cell density (ComA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews


Original Publications

Additional publications: PubMed