Difference between revisions of "ComGB"

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|style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]], DNA uptake
 
|style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]], DNA uptake
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU24720 comGB]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU24720 comGB]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComGB ComGB]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComGB ComGB]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comGC]]'', ''[[comGA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comGC]]'', ''[[comGA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14403&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU24720 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU24720 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU24720 Advanced_DNA]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:comGB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:comGB_context.gif]]

Revision as of 13:17, 13 May 2013

  • Description: polytopic membrane protein , DNA transport machinery

Gene name comGB
Synonyms
Essential no
Product DNA transport machinery
Function genetic competence, DNA uptake
Gene expression levels in SubtiExpress: comGB
Interactions involving this protein in SubtInteract: ComGB
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 36 kDa, 8.654
Gene length, protein length 969 bp, 323 aa
Immediate neighbours comGC, comGA
Sequences Protein DNA Advanced_DNA
Genetic context
ComGB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComGB expression.png
























Categories containing this gene/protein

genetic competence, membrane proteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU24720

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: GSP F family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications

Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147] [WorldCat.org] [DOI] (P p)

Hanne Jarmer, Randy Berka, Steen Knudsen, Hans H Saxild
Transcriptome analysis documents induced competence of Bacillus subtilis during nitrogen limiting conditions.
FEMS Microbiol Lett: 2002, 206(2);197-200
[PubMed:11814663] [WorldCat.org] [DOI] (P p)

Y S Chung, D Dubnau
All seven comG open reading frames are required for DNA binding during transformation of competent Bacillus subtilis.
J Bacteriol: 1998, 180(1);41-5
[PubMed:9422590] [WorldCat.org] [DOI] (P p)

D van Sinderen, A ten Berge, B J Hayema, L Hamoen, G Venema
Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis.
Mol Microbiol: 1994, 11(4);695-703
[PubMed:8196543] [WorldCat.org] [DOI] (P p)

M Albano, R Breitling, D A Dubnau
Nucleotide sequence and genetic organization of the Bacillus subtilis comG operon.
J Bacteriol: 1989, 171(10);5386-404
[PubMed:2507524] [WorldCat.org] [DOI] (P p)