Difference between revisions of "ComA"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU31680
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P14204 P14204]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P14204 P14204]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU31680 BSU31680]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU31680]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/4.4.1.19 4.4.1.19]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/4.4.1.19 4.4.1.19]

Revision as of 14:39, 3 June 2009

  • Description: two-component system response regulator, controls gene expression in response to cell density (concentration of ComX)

Gene name comA
Synonyms srfB, comAA
Essential no
Product two-component system response regulator
Function regulation of genetic competence and quorum sensing
MW, pI 23 kDa, 4.759
Gene length, protein length 642 bp, 214 aa
Immediate neighbours yuxO, comP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ComA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU31680

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (2R)-2-O-phospho-3-sulfolactate = phosphoenolpyruvate + hydrogen sulfite (according to Swiss-Prot)
  • Protein family: ComA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by ComP
  • Cofactor(s):
  • Effectors of protein activity: phosphorylation activates DNA binding
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed