cmk

168

cytidylate kinase (CMP, dCMP)

locus: BSU_22890

Molecular weight: 24.95 kDa

pI: 5

Protein length: 224 aa

Gene length: 675 bp

function: synthesis of CTP and dCTP

product: cytidylate kinase (CMP, dCMP)

essential: yes

ec: 2.7.4.14

synonyms: cmk, jofC, ypfC

List of homologs in different organisms, belongs to COG0283 (Galperin et al., 2021)

Gene

Coordinates: 2,396,045  2,396,719

Phenotypes of a mutant

• essential [Pubmed|12682299]

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The protein

Catalyzed reaction/ biological activity

• ATP + CMP --> ADP + CDP (according to UniProt)
• ATP + dCMP --> ADP + dCDP (according to UniProt)

Protein family

• cytidylate kinase family (single member, according to UniProt)

Structure

• [PDB|1CKE] (from ''Escherichia coli'', 38% identity, 54% similarity) [Pubmed|9862805]
• [AF|P38493]

References

• 9126287