CimH

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  • Description: transporter for citrate and malate

Gene name cimH
Synonyms yxkJ
Essential no
Product proton symporter for citrate and malate
Function transport of organic acids
MW, pI 48 kDa, 6.554
Gene length, protein length 1350 bp, 450 aa
Immediate neighbours
Gene sequence (+200bp) Protein sequence
Genetic context
YxkJ context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: uptake of citrate and malate (symport with protons) PubMed
  • Protein family: 2-hydroxycarboxylate transporter family
  • Paralogous protein(s): MaeN

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Krom et al. (2001) Bacillus subtilis YxkJ is a secondary transporter of the 2-hydroxycarboxylate transporter family that transports L-malate and citrate. J. Bacteriol. 183: 5862-5869. PubMed