Difference between revisions of "CheD"

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* '''Locus tag:''' BSU16460
 
* '''Locus tag:''' BSU16460
 
[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cheD_1715970_1716470_1 Expression]
 
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===

Revision as of 09:14, 28 January 2012

  • Description: required for methylation of methyl-accepting chemotaxis proteins by CheR, enhances phosphatase activity of CheC

Gene name cheD
Synonyms ylxK
Essential no
Product CheC activity modulator
Function motility and chemotaxis
Interactions involving this protein in SubtInteract: CheD
MW, pI 17 kDa, 9.347
Gene length, protein length 498 bp, 166 aa
Immediate neighbours cheC, sigD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CheD context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

CodY regulon, SigD regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU16460

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein L-glutamine + H2O = protein L-glutamate + NH3 (according to Swiss-Prot)
  • Protein family: cheD family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:
    • in minimal medium, CheD is present with 1,200 +/- 250 molecules per cell PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Travis J Muff, George W Ordal
The diverse CheC-type phosphatases: chemotaxis and beyond.
Mol Microbiol: 2008, 70(5);1054-61
[PubMed:18990184] [WorldCat.org] [DOI] (I p)

Christopher V Rao, George D Glekas, George W Ordal
The three adaptation systems of Bacillus subtilis chemotaxis.
Trends Microbiol: 2008, 16(10);480-7
[PubMed:18774298] [WorldCat.org] [DOI] (P p)

Original publications