Difference between revisions of "CheC"

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* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
  
* '''Effectors of protein activity:'''
+
* '''Effectors of protein activity:''' interaction with [[CheD]] enhances phosphatase activity towards [[CheY]]-P {{PubMed|17908686}}
  
* '''Interactions:''' [[McpB]]-[[CheC]], [[CheA]]-[[CheC]], [[CheC]]-[[CheD]], [[CheC]]-[[CheY]]-P
+
* '''Interactions:''' [[McpB]]-[[CheC]] {{PubMed|11722727}}, [[CheA]]-[[CheC]] {{PubMed|11722727}}, [[CheC]]-[[CheD]] {{PubMed|17908686}}, [[CheC]]-[[CheY]]-P
  
 
* '''Localization:'''
 
* '''Localization:'''
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** [[Spo0A]]: transcription repression {{PubMed|14651647}}
 
** [[Spo0A]]: transcription repression {{PubMed|14651647}}
 
** [[CodY]]: transcription repression {{PubMed|12730172}}
 
** [[CodY]]: transcription repression {{PubMed|12730172}}
 +
** [[DegU]] (non-phosphorylated): transcription activation {{PubMed|17850253}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
 
+
<pubmed>7893679,14993307,18774298,8866475,18990184,17908686,14749334,11722727,9194713, 14651647, 9657996,8157612, 15175317,17609139, 16469702, 20080618,17675386,20133180 17850253</pubmed>
<pubmed>7893679,14993307,18774298,8866475,18990184,17908686,14749334,11722727,9194713, 14651647, 9657996,8157612,15175317,17609139,16469702,20080618,17675386,20133180</pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:25, 31 July 2010

  • Description: CheY-P phosphatase, inhibition of CheR-mediated methylation of MCPs

Gene name cheC
Synonyms ylxJ
Essential no
Product CheY-P phosphatase
Function motility, chemotaxis
MW, pI 22 kDa, 4.035
Gene length, protein length 627 bp, 209 aa
Immediate neighbours cheW, cheD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CheC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU16450

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: CheY phosphatase, CheD regulation
  • Protein family: cheC family (according to Swiss-Prot)
  • Paralogous protein(s):FliY

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: interaction with CheD enhances phosphatase activity towards CheY-P PubMed
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References