Difference between revisions of "CatR"

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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
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|style="background:#ABCDEF;" align="center"| '''Product''' || transcription repressor  
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|style="background:#ABCDEF;" align="center"| '''Product''' || MarR/DUF24-family transcription repressor  
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || Resistance against oxidative and electrophile stress
 
|style="background:#ABCDEF;" align="center"|'''Function''' || Resistance against oxidative and electrophile stress

Revision as of 15:15, 15 December 2011

  • Description: MarR/DUF24-family transcription repressor of the catD-catE operon

Gene name yvaP
Synonyms
Essential no
Product MarR/DUF24-family transcription repressor
Function Resistance against oxidative and electrophile stress
MW, pI 26 kDa, 9.887
Gene length, protein length 708 bp, 236 aa
Immediate neighbours yvaO, yvaQ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvaP context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

The CatR regulon:

catD-catE

The gene

Basic information

  • Locus tag: BSU33680

Phenotypes of a mutant

increased resistance to catechol and quinones PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: MarR/DUF24-family transcription repressor of the catD-catE operon PubMed
  • Protein family:
  • Paralogous protein(s): YodB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: in responsse to the presence of diamides or quinones, Cys-7 forms intermolecular disulfide bonds, this results in loss of DNA-bindig ability (induction of catD-catE) PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Bui Khanh Chi, Kazuo Kobayashi, Dirk Albrecht, Michael Hecker, Haike Antelmann
The paralogous MarR/DUF24-family repressors YodB and CatR control expression of the catechol dioxygenase CatE in Bacillus subtilis.
J Bacteriol: 2010, 192(18);4571-81
[PubMed:20639328] [WorldCat.org] [DOI] (I p)