CapE

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  • Description: stimulates poly-gamma-glutamate production in the presence of zinc, also involved in extra-chromosomal DNA maintenance

Gene name capE
Synonyms ywtC, pgsE, edmS
Essential no
Product unknown
Function capsule synthesis
Gene expression levels in SubtiExpress: capE
MW, pI 6 kDa, 6.487
Gene length, protein length 165 bp, 55 aa
Immediate neighbours pgdS, capA
Sequences Protein DNA DNA_with_flanks
Genetic context
YwtC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CapE expression.png















Categories containing this gene/protein

capsule biosynthesis and degradation, membrane proteins

This gene is a member of the following regulons

DegU regulon

The gene

Basic information

  • Locus tag: BSU35870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • stimulates poly-gamma-glutamate production in the presence of zinc PubMed
    • also involved in extra-chromosomal DNA maintenance PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: N-terminal membrane-anchoring domain and a C-terminal assembly accelerator-like structure PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information: The operon is not expressed in the lab strain 168 due to lack of expression of DegQ resulting in inactivity of DegS and DegU PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Thomas Candela, Agnès Fouet
Poly-gamma-glutamate in bacteria.
Mol Microbiol: 2006, 60(5);1091-8
[PubMed:16689787] [WorldCat.org] [DOI] (P p)

Original publications