Difference between revisions of "CapE"

From SubtiWiki
Jump to: navigation, search
Line 6: Line 6:
 
|''capE''
 
|''capE''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ywtC, pgsE''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ywtC, pgsE, edmS''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
Line 35: Line 35:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
 
 
<br/><br/>
 
<br/><br/>
  
 
= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[capsule biosynthesis and degradation]]}}
+
{{SubtiWiki category|[[capsule biosynthesis and degradation]]}},
 +
{{SubtiWiki category|[[membrane proteins]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
Line 70: Line 67:
 
=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' stimulates poly-gamma-glutamate production in the presence of zinc {{PubMed|20812257}}, also involved in extra-chromosomal DNA maintenance {{PubMed|21357437}}
+
* '''Catalyzed reaction/ biological activity:'''  
 +
** stimulates poly-gamma-glutamate production in the presence of zinc {{PubMed|20812257}}
 +
** also involved in extra-chromosomal DNA maintenance {{PubMed|23583563,21357437}}
  
 
* '''Protein family:'''
 
* '''Protein family:'''
Line 80: Line 79:
 
* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''Domains:''' N-terminal membrane-anchoring domain and a C-terminal assembly accelerator-like structure {{PubMed|23583563}}
  
 
* '''Modification:'''
 
* '''Modification:'''
Line 91: Line 90:
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
 +
** cell membrane {{PubMed|23583563}}
  
 
=== Database entries ===
 
=== Database entries ===
Line 110: Line 110:
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pgsE_3697639_3697806_-1 capE] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pgsE_3697639_3697806_-1 capE] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19420703 PubMed]
+
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19420703 PubMed]
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
Line 137: Line 137:
  
 
=References=
 
=References=
'''Additional publications:''' {{PubMed|20812257,21965392}}
+
<pubmed>19420703, 16233197 16267300 20564357 20564574 21357437 23583563 20812257,21965392</pubmed>
<pubmed>19420703, 16233197 16267300 20564357 20564574 21357437</pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:55, 19 April 2013

  • Description: stimulates poly-gamma-glutamate production in the presence of zinc, also involved in extra-chromosomal DNA maintenance

Gene name capE
Synonyms ywtC, pgsE, edmS
Essential no
Product unknown
Function capsule synthesis
Gene expression levels in SubtiExpress: capE
MW, pI 6 kDa, 6.487
Gene length, protein length 165 bp, 55 aa
Immediate neighbours pgdS, capA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwtC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CapE expression.png















Categories containing this gene/protein

capsule biosynthesis and degradation, membrane proteins

This gene is a member of the following regulons

DegU regulon

The gene

Basic information

  • Locus tag: BSU35870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • stimulates poly-gamma-glutamate production in the presence of zinc PubMed
    • also involved in extra-chromosomal DNA maintenance PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: N-terminal membrane-anchoring domain and a C-terminal assembly accelerator-like structure PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information: The operon is not expressed in the lab strain 168 due to lack of expression of DegQ resulting in inactivity of DegS and DegU PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References