Difference between revisions of "Buk"

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* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10094682 PubMed]
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10094682 PubMed]
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 11:50, 11 June 2009

  • Description: butyrate kinase

Gene name buk
Synonyms yqiU, bkd
Essential no
Product butyrate kinase
Function utilization of branched-chain keto acids
MW, pI 39 kDa, 5.466
Gene length, protein length 1089 bp, 363 aa
Immediate neighbours lpdV, bcd
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Buk context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU24070

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + butanoate = ADP + butanoyl phosphate (according to Swiss-Prot)
  • Protein family: acetokinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed