Difference between revisions of "BsrA"

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(References)
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* '''Operon:''' ''bsrA''  [http://www.ncbi.nlm.nih.gov/sites/entrez/12177353 PubMed]
 
* '''Operon:''' ''bsrA''  [http://www.ncbi.nlm.nih.gov/sites/entrez/12177353 PubMed]
  
* '''Sigma factor:''' [[SigA]]  [http://www.ncbi.nlm.nih.gov/sites/entrez/12177353 PubMed]
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* '''[[Sigma factor]]:''' [[SigA]]  [http://www.ncbi.nlm.nih.gov/sites/entrez/12177353 PubMed]
  
 
* '''Regulation:''' expressed in vegetative cells  [http://www.ncbi.nlm.nih.gov/sites/entrez/12177353 PubMed]
 
* '''Regulation:''' expressed in vegetative cells  [http://www.ncbi.nlm.nih.gov/sites/entrez/12177353 PubMed]
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=References=
 
=References=
'''Additional publications:''' {{PubMed|23457253,22333917,21881410,22102588}}
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<pubmed>12177353 15811922 23457253,22333917,21881410,22102588 23761441 </pubmed>
<pubmed>12177353 15811922 </pubmed>
 
  
 
[[Category:small RNA]]
 
[[Category:small RNA]]

Revision as of 14:06, 14 June 2013

  • Description: 6S RNA, important for timing of sporulation

Gene name bsrA
Synonyms
Essential no
Product 6S RNA
Function antagonist of SigA
Interactions involving this RNA in SubtInteract: BsrA
Gene length 190 bp
Immediate neighbours yrvM, aspS
Gene sequence (+200bp)
Genetic context
BsrA context.jpeg








Categories containing this gene/protein

sigma factors and their control, ncRNA

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU_misc_RNA_41

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: no entry
  • Structure:

Additional information

Expression and regulation

  • Regulation: expressed in vegetative cells PubMed
  • Regulatory mechanism:
  • Additional information: transcribed as 201 nt RNA, processed to mature 190 bp 6S RNA PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:


Labs working on this gene/RNA

Kouji Nakamura, Tsukuba, University, Japan

Roland Hartmann, Philipps-Universität Marburg, Marburg, Germany, Homepage

Your additional remarks

References

Ignacio J Cabrera-Ostertag, Amy T Cavanagh, Karen M Wassarman
Initiating nucleotide identity determines efficiency of RNA synthesis from 6S RNA templates in Bacillus subtilis but not Escherichia coli.
Nucleic Acids Res: 2013, 41(15);7501-11
[PubMed:23761441] [WorldCat.org] [DOI] (I p)

Amy T Cavanagh, Karen M Wassarman
6S-1 RNA function leads to a delay in sporulation in Bacillus subtilis.
J Bacteriol: 2013, 195(9);2079-86
[PubMed:23457253] [WorldCat.org] [DOI] (I p)

Benedikt M Beckmann, Philipp G Hoch, Manja Marz, Dagmar K Willkomm, Margarita Salas, Roland K Hartmann
A pRNA-induced structural rearrangement triggers 6S-1 RNA release from RNA polymerase in Bacillus subtilis.
EMBO J: 2012, 31(7);1727-38
[PubMed:22333917] [WorldCat.org] [DOI] (I p)

Amy T Cavanagh, Jamie M Sperger, Karen M Wassarman
Regulation of 6S RNA by pRNA synthesis is required for efficient recovery from stationary phase in E. coli and B. subtilis.
Nucleic Acids Res: 2012, 40(5);2234-46
[PubMed:22102588] [WorldCat.org] [DOI] (I p)

Benedikt M Beckmann, Olga Y Burenina, Philipp G Hoch, Elena A Kubareva, Cynthia M Sharma, Roland K Hartmann
In vivo and in vitro analysis of 6S RNA-templated short transcripts in Bacillus subtilis.
RNA Biol: 2011, 8(5);839-49
[PubMed:21881410] [WorldCat.org] [DOI] (I p)

Jeffrey E Barrick, Narasimhan Sudarsan, Zasha Weinberg, Walter L Ruzzo, Ronald R Breaker
6S RNA is a widespread regulator of eubacterial RNA polymerase that resembles an open promoter.
RNA: 2005, 11(5);774-84
[PubMed:15811922] [WorldCat.org] [DOI] (P p)

Satoru Suzuma, Sayaka Asari, Keigo Bunai, Keiko Yoshino, Yoshinari Ando, Hiroshi Kakeshita, Masaya Fujita, Kouji Nakamura, Kunio Yamane
Identification and characterization of novel small RNAs in the aspS-yrvM intergenic region of the Bacillus subtilis genome.
Microbiology (Reading): 2002, 148(Pt 8);2591-2598
[PubMed:12177353] [WorldCat.org] [DOI] (P p)