Difference between revisions of "BpsA"

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=== Additional information===
 
=== Additional information===
 
 
  
  
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bcsA_2316956_2318053_-1 bpsA] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bcsA_2316956_2318053_-1 bpsA] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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=Biological materials =
 
=Biological materials =
  
* '''Mutant:'''
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* '''Mutant:''' BKE22050 (''[[bpsA]]''::''erm'', available in the BGSC and in [[Jörg Stülke]]'s lab)
  
 
* '''Expression vector:'''
 
* '''Expression vector:'''

Revision as of 18:48, 1 February 2015

  • Description: type III polyketide synthase

Gene name bpsA
Synonyms bcsA
Essential no
Product type III polyketide synthase
Function polyketide synthesis
Gene expression levels in SubtiExpress: bpsA
MW, pI 40 kDa, 7.958
Gene length, protein length 1095 bp, 365 aa
Immediate neighbours bpsB, pbuX
Sequences Protein DNA DNA_with_flanks
Genetic context
BcsA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
BpsA expression.png















Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds, membrane proteins, sporulation proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU22050

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: synthesis of triketide pyrones from long-chain fatty acyl CoA thioesters as starter substrates and malonyl-CoA as an extender substrate PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Chiaki Nakano, Hiroki Ozawa, Genki Akanuma, Nobutaka Funa, Sueharu Horinouchi
Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis.
J Bacteriol: 2009, 191(15);4916-23
[PubMed:19465653] [WorldCat.org] [DOI] (I p)