Difference between revisions of "BpsA"

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Revision as of 11:49, 19 April 2012

  • Description: type III polyketide synthase

Gene name bpsA
Synonyms bcsA
Essential no
Product type III polyketide synthase
Function polyketide synthesis
MW, pI 40 kDa, 7.958
Gene length, protein length 1095 bp, 365 aa
Immediate neighbours bpsB, pbuX
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
BcsA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
BpsA expression.png
























Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU22050

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: synthesis of triketide pyrones from long-chain fatty acyl CoA thioesters as starter substrates and malonyl-CoA as an extender substrate PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Chiaki Nakano, Hiroki Ozawa, Genki Akanuma, Nobutaka Funa, Sueharu Horinouchi
Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis.
J Bacteriol: 2009, 191(15);4916-23
[PubMed:19465653] [WorldCat.org] [DOI] (I p)