Difference between revisions of "BmrR"

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* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2BOW 2BOW] (complex with effector),  [http://www.rcsb.org/pdb/explore.do?structureId=1R8E 1R8E] (complex with DNA),  [http://www.rcsb.org/pdb/explore.do?structureId=1BOW 1BOW]
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2BOW 2BOW] (complex with effector),  [http://www.rcsb.org/pdb/explore.do?structureId=1R8E 1R8E] (complex with DNA),  [http://www.rcsb.org/pdb/explore.do?structureId=1BOW 1BOW]
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39075 P39075]
+
* '''UniProt:''' [http://www.uniprot.org/uniprot/P39075 P39075]
  
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU24020]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU24020]

Revision as of 13:29, 20 July 2009

  • Description: general stress protein, transcriptional activator of the bmrU-bmrR operon

Gene name bmrR
Synonyms
Essential no
Product transcriptional activator
Function regulation of multidrug resistance
MW, pI 32 kDa, 5.187
Gene length, protein length 834 bp, 278 aa
Immediate neighbours bmr, bkdB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
BmrR context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU24020

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure: 2BOW (complex with effector), 1R8E (complex with DNA), 1BOW
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Brennan, Houston, Texas, USA Homepage

Your additional remarks

References

A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224] [WorldCat.org] [DOI] (P p)

M Ahmed, L Lyass, P N Markham, S S Taylor, N Vázquez-Laslop, A A Neyfakh
Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated.
J Bacteriol: 1995, 177(14);3904-10
[PubMed:7608059] [WorldCat.org] [DOI] (P p)