BlyA

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  • Description: N-acetylmuramoyl-L-alanine amidase

Gene name blyA
Synonyms yomC
Essential no
Product N-acetylmuramoyl-L-alanine amidase
Function SPß-mediated lysis
MW, pI 39 kDa, 9.935
Gene length, protein length 1101 bp, 367 aa
Immediate neighbours yomD, bhlA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
BlyA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell wall degradation/ turnover, SP-beta prophage

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU21410

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Alexandre Regamey, Dimitri Karamata
The N-acetylmuramoyl-L-alanine amidase encoded by the Bacillus subtilis 168 prophage SP beta.
Microbiology (Reading): 1998, 144 ( Pt 4);885-893
[PubMed:9579063] [WorldCat.org] [DOI] (P p)