Biosynthesis of cofactors

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Genes in this functional category

Biosynthesis/ acquisition of biotin

Biosynthesis/ acquisition of riboflavin/ fad

Biosynthesis/ acquisition of thiamine

Biosynthesis/ acquisition of thiamine/ based on similarity

Biosynthesis of coenzyme a

Biosynthesis of folate

Biosynthesis of heme/ siroheme

Biosynthesis of lipoic acid

Biosynthesis of menaquinone

Biosynthesis of menaquinone/ based on similarity

Biosynthesis of molybdopterin

Biosynthesis of nad(p)

Biosynthesis of pyridoxal phosphate

Metabolism of cofactors in SubtiPathways

CoA synthesis

Folate biosynthesis

Menaquinone

Riboflavin and FAD synthesis

Thiamin synthesis

Biotin synthesis

Important reviews

Christopher T Jurgenson, Tadhg P Begley, Steven E Ealick
The structural and biochemical foundations of thiamin biosynthesis.
Annu Rev Biochem: 2009, 78;569-603
[PubMed:19348578] [WorldCat.org] [DOI] (I p)

Tadhg P Begley, Abhishek Chatterjee, Jeremiah W Hanes, Amrita Hazra, Steven E Ealick
Cofactor biosynthesis--still yielding fascinating new biological chemistry.
Curr Opin Chem Biol: 2008, 12(2);118-25
[PubMed:18314013] [WorldCat.org] [DOI] (P p)

Ethan Settembre, Tadhg P Begley, Steven E Ealick
Structural biology of enzymes of the thiamin biosynthesis pathway.
Curr Opin Struct Biol: 2003, 13(6);739-47
[PubMed:14675553] [WorldCat.org] [DOI] (P p)

A Marquet, B T Bui, D Florentin
Biosynthesis of biotin and lipoic acid.
Vitam Horm: 2001, 61;51-101
[PubMed:11153271] [WorldCat.org] [DOI] (P p)

T P Begley, D M Downs, S E Ealick, F W McLafferty, A P Van Loon, S Taylor, N Campobasso, H J Chiu, C Kinsland, J J Reddick, J Xi
Thiamin biosynthesis in prokaryotes.
Arch Microbiol: 1999, 171(5);293-300
[PubMed:10382260] [WorldCat.org] [DOI] (P p)