Difference between revisions of "BglP"
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* '''[[Sigma factor]]:''' [[SigA]] | * '''[[Sigma factor]]:''' [[SigA]] | ||
| − | * '''Regulation:''' repressed by glucose ([[CcpA]]) | + | * '''Regulation:''' |
| + | ** repressed by glucose ([[CcpA]], [[LicT]]) | ||
| + | ** induced by salicin ([[LicT]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7883710 PubMed] | ||
| − | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression, | + | * '''Regulatory mechanism:''' |
| + | ** [[CcpA]]: transcription repression, ([[CcpA]] binding site overlaps -35 region) | ||
| + | ** [[LicT]]-dependent [[RNA switch]] (antitermination, lack of [[LicT]]-dependent antitermination in the presence of gucose due to the requirement of [[LicT]] to be phosphorylated by [[PtsH| HPr]] | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 21:03, 8 June 2009
- Description: trigger enzyme: beta-glucoside-specific phosphotransferase system, EIIBC
| Gene name | bglP |
| Synonyms | sytA |
| Essential | no |
| Product | trigger enzyme: beta-glucoside-specific phosphotransferase system, EIIBC |
| Function | beta-glucoside uptake and phosphorylation, control of LicT activity |
| MW, pI | 64 kDa, 6.809 |
| Gene length, protein length | 1827 bp, 609 aa |
| Immediate neighbours | bglH, yxxE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU39270
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)
- Protein family: PTS permease, sucrose permease (Scr) family PubMed
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P40739
- KEGG entry: [3]
- E.C. number: 2.7.1.69 9
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jonathan Reizer, Steffi Bachem, Aiala Reizer, Maryvonne Arnaud, Milton H Saier, Jörg Stülke
Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 12);3419-3429
[PubMed:10627040]
[WorldCat.org]
[DOI]
(P p)
S Krüger, S Gertz, M Hecker
Transcriptional analysis of bglPH expression in Bacillus subtilis: evidence for two distinct pathways mediating carbon catabolite repression.
J Bacteriol: 1996, 178(9);2637-44
[PubMed:8626332]
[WorldCat.org]
[DOI]
(P p)
S Krüger, M Hecker
Regulation of the putative bglPH operon for aryl-beta-glucoside utilization in Bacillus subtilis.
J Bacteriol: 1995, 177(19);5590-7
[PubMed:7559347]
[WorldCat.org]
[DOI]
(P p)
D Le Coq, C Lindner, S Krüger, M Steinmetz, J Stülke
New beta-glucoside (bgl) genes in Bacillus subtilis: the bglP gene product has both transport and regulatory functions similar to those of BglF, its Escherichia coli homolog.
J Bacteriol: 1995, 177(6);1527-35
[PubMed:7883710]
[WorldCat.org]
[DOI]
(P p)
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
