BglC

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  • Description: endo-1,4-beta-glucanase

Gene name bglC
Synonyms eglS
Essential no
Product endo-1,4-beta-glucanase)
Function beta-1,4-glucan degradation
MW, pI 55 kDa, 8.619
Gene length, protein length 1497 bp, 499 aa
Immediate neighbours alsT, ynfE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
BglC context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU18130

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans (according to Swiss-Prot)
  • Protein family: glycosyl hydrolase 5 (cellulase A) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1H2J (from Bacillus agaradhaerens)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon: bglC (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

L M Robson, G H Chambliss
Endo-beta-1,4-glucanase gene of Bacillus subtilis DLG.
J Bacteriol: 1987, 169(5);2017-25
[PubMed:3106328] [WorldCat.org] [DOI] (P p)

R M MacKay, A Lo, G Willick, M Zuker, S Baird, M Dove, F Moranelli, V Seligy
Structure of a Bacillus subtilis endo-beta-1,4-glucanase gene.
Nucleic Acids Res: 1986, 14(22);9159-70
[PubMed:3024130] [WorldCat.org] [DOI] (P p)