Difference between revisions of "BdbD"

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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
  
* '''Localization:''' membrane, faced to the outer side of the membrane  [http://www.ncbi.nlm.nih.gov/sites/entrez/19535335 PubMed]
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* '''[[Localization]]:''' membrane, faced to the outer side of the membrane  [http://www.ncbi.nlm.nih.gov/sites/entrez/19535335 PubMed]
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 09:55, 16 July 2011

  • Description: thiol-disulfide oxidoreductase, required for the formation of thiol disulfide bonds in ComGC

Gene name bdbD
Synonyms yvgV
Essential no
Product thiol-disulfide oxidoreductase
Function genetic transformation
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 24 kDa, 5.089
Gene length, protein length 666 bp, 222 aa
Immediate neighbours bdbC, cadA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
BdbD context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

genetic competence, chaperones/ protein folding, sporulation proteins, membrane proteins

This gene is a member of the following regulons

ComK regulon, SigE regulon

The gene

Basic information

  • Locus tag: BSU33480

Phenotypes of a mutant

loss of transformability PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: formation of thiol disulfide bonds in ComGC PubMed
  • Protein family: DsbA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the mother cell (SigE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References