Difference between revisions of "BcrC"

From SubtiWiki
Jump to: navigation, search
Line 35: Line 35:
 
=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU36530
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
Line 80: Line 80:
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94571 P94571]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94571 P94571]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU36530 BSU36530]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU36530]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''

Revision as of 09:15, 3 June 2009

  • Description: undecaprenyl pyrophosphate phosphatase, bacitracin resistance

Gene name bcrC
Synonyms ywoA
Essential no
Product undecaprenyl pyrophosphate phosphatase
Function resistance to bacitracin and oxidative stress
MW, pI 21 kDa, 9.455
Gene length, protein length 579 bp, 193 aa
Immediate neighbours nrgB, ywnJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwoA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU36530

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bcrC/ybjG/ywoA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: bcrC
  • Regulation: expression activated by glucose (3.3 fold) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
  2. Jervis et al. 2007. SigM-responsive genes of Bacillus subtilis and their promoters. J. Bacteriol. 189: 4534-4538. PubMed
  3. Tseng, C. L., and Shaw, G. C. (2008) Genetic evidence for the actin homolog gene mreBH and the bacitracin resistance gene bcrC as targets of the alternative sigma factor SigI of Bacillus subtilis. J. Bacteriol. 190: 1561-1567. PubMed
  4. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed