Difference between revisions of "BceA"

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(References)
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* '''Description:''' bacitracin ABC transporter (ATP-binding protein) for bacitracin export <br/><br/>
+
* '''Description:''' bacitracin [[ABC transporter]] (ATP-binding protein) for bacitracin export <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || bacitracin ABC transporter (ATP-binding protein)  
+
|style="background:#ABCDEF;" align="center"| '''Product''' || bacitracin [[ABC transporter]] (ATP-binding protein)  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || bacitracin export
 
|style="background:#ABCDEF;" align="center"|'''Function''' || bacitracin export
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:''' ABC transporter family (according to Swiss-Prot)
+
* '''Protein family:''' [[ABC transporter]] family (according to Swiss-Prot)
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''Interactions:''' [[BceA]]-[[BceB]] {{PubMed|10092453}}
  
* '''Localization:'''
+
* '''Localization:''' membrane associated (via [[BceB]]) {{PubMed|10092453}}
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 20:12, 14 January 2010

  • Description: bacitracin ABC transporter (ATP-binding protein) for bacitracin export

Gene name ytsC
Synonyms bceA
Essential no
Product bacitracin ABC transporter (ATP-binding protein)
Function bacitracin export
MW, pI 28 kDa, 9.287
Gene length, protein length 759 bp, 253 aa
Immediate neighbours bceB, bceS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtsC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU30380

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: membrane associated (via BceB) PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced in the presence of bacitracin (BceR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Foglino M. PubMed

Your additional remarks

References

Eva Rietkötter, Diana Hoyer, Thorsten Mascher
Bacitracin sensing in Bacillus subtilis.
Mol Microbiol: 2008, 68(3);768-85
[PubMed:18394148] [WorldCat.org] [DOI] (I p)

Remi Bernard, Annick Guiseppi, Marc Chippaux, Maryline Foglino, François Denizot
Resistance to bacitracin in Bacillus subtilis: unexpected requirement of the BceAB ABC transporter in the control of expression of its own structural genes.
J Bacteriol: 2007, 189(23);8636-42
[PubMed:17905982] [WorldCat.org] [DOI] (I p)

Thorsten Mascher, Neil G Margulis, Tao Wang, Rick W Ye, John D Helmann
Cell wall stress responses in Bacillus subtilis: the regulatory network of the bacitracin stimulon.
Mol Microbiol: 2003, 50(5);1591-604
[PubMed:14651641] [WorldCat.org] [DOI] (P p)

Reiko Ohki, Giyanto, Kozue Tateno, Waka Masuyama, Shigeki Moriya, Kazuo Kobayashi, Naotake Ogasawara
The BceRS two-component regulatory system induces expression of the bacitracin transporter, BceAB, in Bacillus subtilis.
Mol Microbiol: 2003, 49(4);1135-44
[PubMed:12890034] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)