bacB
168
oxidase that catalyzes the synthesis of 2-oxo-3-(4-oxocyclohexa-2,5-dienyl)propanoic acid, a precursor to L-anticapsin
locus
BSU_37730
Molecular weight
26.69 kDa
pI
5.19
function
biosynthesis of the antibiotic bacilysin
product
oxidase
essential
no
synonyms
bacB, ywfC, ipa-81d
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1917 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,872,869 3,873,576
The protein
Catalyzed reaction/ biological activity
synthesis of 2-oxo-3-(4-oxocyclohexa-2,5-dienyl)propanoic acid, a precursor to L-anticapsin [Pubmed|19776011]
3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate --> 3-[(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene]pyruvate (according to UniProt)
[wiki|Domains]
2 [wiki|cupin 2 domain]s (aa 41 ... 106, aa 151 ... 216)
Structure
[PDB|3H7J] [Pubmed|19776011]
[AF|P39639]
Biological materials
Mutant
MGNA-B240 (ywfC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1239 NBRP B. subtilis, Japan]
BKE37730 ([gene|0EEE23875DB720D256D53F00D1AD5EF24B538B27|bacB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE37730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GAAATAAAGCTCCTGCATAT, downstream forward: _UP4_AAAATGAAGGCGGATGAATG
BKK37730 ([gene|0EEE23875DB720D256D53F00D1AD5EF24B538B27|bacB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK37730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GAAATAAAGCTCCTGCATAT, downstream forward: _UP4_AAAATGAAGGCGGATGAATG
References
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Time of last update: 2024-04-24 12:59:23
Author of last update: Melvin.boenninger