argS

argS
168

arginyl-tRNA synthetase, universally conserved protein

locus
BSU_37330
Molecular weight
62.55 kDa
pI
5.11
Protein length
Gene length
function
translation
product
arginyl-tRNA synthetase
essential
yes
ec
6.1.1.19
synonyms
argS

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0018 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,833,650  3,835,320
Phenotypes of a mutant
essential [Pubmed|12682299]
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The protein
Catalyzed reaction/ biological activity
ATP + L-arginine + tRNAArg --> AMP + diphosphate + L-arginyl-tRNAArg (according to UniProt)
Protein family
[wiki|Class-I aminoacyl-tRNA synthetase family] (according to UniProt)
Structure
[PDB|3FNR] (from ''Campylobacter jejuni'', 39% identity, 56% similarity)
[AF|P46906]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Additional information
[wiki|universally conserved protein]
Expression and Regulation
Operons
genes
[gene|83721D87607FE6448C2C0D17E401C87C57A05AF8|argS]
description
[Pubmed|9353933]
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[gene|83721D87607FE6448C2C0D17E401C87C57A05AF8|argS]

2024-01-26 18:24:11

ghost

41

18cd2aeffbb7a9518dbb385e72dab52226690fdd

408B5282DBF389759A0D38715A4EE6DFAB5B7436

genes
[gene|D71F54220FCC2B687857F53F53584D6CB90650CD|ywiB]-[gene|83721D87607FE6448C2C0D17E401C87C57A05AF8|argS]
description
[Pubmed|22383849]
Open in new tab

[gene|D71F54220FCC2B687857F53F53584D6CB90650CD|ywiB]→[gene|83721D87607FE6448C2C0D17E401C87C57A05AF8|argS]

2024-02-18 12:30:32

Jstuelk

67

5835d85829be98992c614fac729adc6bf7a5bc02

9B446A3046E5C4192FEB5128DA43B807DA3DE3BC

additional information
the mRNA is cleaved by [protein|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|RNase III] [PubMed|26883633]
Biological materials
Expression vectors
pGP2897: expression of Strep-''argS'' by [wiki|pGP380] in ''B. subtilis'' suitable for [wiki|SPINE], available in [wiki|Jörg Stülke]'s lab
References
36815589,9353933,26883633

83721D87607FE6448C2C0D17E401C87C57A05AF8

Page visits: 2262

Time of last update: 2024-03-27 18:41:15

Author of last update: Jstuelk