yurI

168

ribonuclease, extracellular RNase Bsn

locus: BSU_32540

Molecular weight: 31.94 kDa

pI: 4.87

Protein length: 288 aa

Gene length: 867 bp

function: extracellular RNA degradation

product: extracellular RNase Bsn

essential: no

ec: null

synonyms: yurI

List of homologs in different organisms, belongs to COG2356 (Galperin et al., 2021)

Gene

Coordinates: 3,344,113  3,344,979

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The protein

Structure

• [AF|O32150]

[wiki|Localization]

• extracellular (signal peptide) [Pubmed|18957862]

Expression and Regulation

Operons

• genes: [gene|4D46B2842D6B8B8002F47544E76DB36C24364E69|yurI]

  description: [Pubmed|16291680]

  regulation

  • expressed under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|16291680]

  regulatory mechanism

  • [protein|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|phoP]: activation, [Pubmed|16291680], in [regulon|protein:638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|phoP regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]

Biological materials

Mutant

• MGNA-A552 (yurI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/552 NBRP B. subtilis, Japan]
• BKE32540 ([gene|4D46B2842D6B8B8002F47544E76DB36C24364E69|yurI]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE32540 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCACTTGCCCTCCTTTTA,  downstream forward: _UP4_TAAGAAAAAGGTGCTCCTTT
• BKK32540 ([gene|4D46B2842D6B8B8002F47544E76DB36C24364E69|yurI]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK32540 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCACTTGCCCTCCTTTTA,  downstream forward: _UP4_TAAGAAAAAGGTGCTCCTTT

References

Reviews

• 31464530

Original Publications

• 16291680,18957862,12490701,1396690,20709850,20817675,25666134